11. Ron Lester

The next transformation in our list is Ron Lester, who is well-known for playing Billy Bob in Varsity Blues. He has always taken on parts that fit his large frame. Ron Lester weighed about 500 pounds at his heaviest. In the year 2000, he had a change of heart and become serious to lose weight. So, he started with gastric bypass surgery. He was able to reduce his weight to 193 pounds after the surgery.